1. Zuo Z, Song Q, Cheng SW, Zou J, Yang X and Shaw PC (2024). Comparison on metabolic fate of dendrobium polysaccharides in gut microbiota fermentation process between healty and diabetic status. Drug Metabolism and Pharmacokinetics, 55, p.100840.
  2. Zou J, Song Q, Shaw PC, Zuo Z (2024). Dendrobium officinale regulate lipid metabolism in diabetic mouse liver via PPAR-RXR signaling pathway: Evidence from an integrated multi-omics analysis. Biomedicine & Pharmacotherapy, 173:116395.
  3. Song Q, Cheng SW, Zou J, Li SLK, Cheng H, Lau DTW, Han Q, Yang X, Shaw PC, Zuo Z (2024). Role of gut microbiota on regulation potential of Dendrobium officinale Kimura & Migo in metabolic syndrome: In-vitro fermentation screening and in-vivo verification in db/db mice. Journal of Ethnopharmacology. 321:117437. 
  4. Kan LLY, Chan BCL, Yue GGL, Li, P, Hon SSM, Huang D, Tsang MSM, Lau CBS, Leung PC, Wong CK (2024). Immunoregulatory and Anti-cancer Activities of Combination Treatment of Novel Four-Herb Formula and Doxorubicin in 4T1-Breast Cancer Bearing Mice. Chinese Journal of Integrative Medicine. 30: 311-321.
  5. Wang D, Chan BCL, Zhang B, Wong KCY, Kan LLY, Wong CK (2024). Dark under the Lamp: Neglected Biological Pollutants in the Environment Are Closely Linked to Lung Cancer. International Journal of Molecular Sciences, 25(6), 3081.
  6. Wang D, Zhang B, Liu X, Kan LLY, Leung PC, Wong CK (2024). Agree to disagree: the contradiction between IL-18 and IL-37 reveals shared targets in cancer. Pharmacological Research, 107072. 
  7. Chan BCL, Li P, Tsang MSM, Sung JCC, Kwong KWY, Zheng T, Hon SSM, Lau CP, Ho RCY, Chen F, Lau CBS, Leung PC, Wong CK (2024). Adjuvant activities of immunostimulating natural products: Astragalus membranaceus (Fisch.) Bge. and Coriolus versicolor in BNT162b2 vaccination against COVID-19 infection. Journal of Leukocyte Biology, 115(1), 177-189. 
  8. Wu HY, Wong KL, Law STS, Nong W, Chan KT, Hui JHL, Lin G, Chan WH, Shaw PC (2024). Determination of ITS1 haplotypes of Fritillariae Cirrhosae Bulbus by amplicon sequencing. Chinese Medicine, 19(1), p.33.
  9. So WL, Chong TK, Lee IHT, So MTW, Liu AMY, Leung STC, Ching W, Yip HY, Shaw PC, Hui, JHL (2024). Cytochrome oxidase I DNA barcodes of crocodilians meat selling in Hong Kong. Scientific Data, 11(1), p.46. 
  10. Wachananawat B, Kong BLH, Shaw PC, Bongcheewin B, Sangvirotjanapat S, Prombutara P, Pornputtapong N, Sukrong, S. (2024). Characterization and phylogenetic analysis of the complete chloroplast genome of Curcuma comosa and latifolia. Heliyon. 10, e31248.
  11. Wong KH, Zheng T, Yue GGL, Li MC, Wu HY, Tong MH, Zhao XL, Chen HB, Lau CBS, Shaw PC, Lau DTW (2024). A systematic approach for authentication of medicinal Patrinia species using an integration of morphological, chemical and molecular methods. Scientific Reports, 14(1), 6566.
  12. Chan KT, Wu HY, Tin WY, But PPH, Cheung SCH, Shaw PC (2024). Ethnopharmacology of five flowers herbal tea, a popular traditional beverage in Hong Kong and South China. Journal of Ethnobiology and Ethnomedicine, 20(1), 36.



  1. Tang YS, Zhang C, Lo CY, Jin Z, Kong BLH, Xiao MJ, Huang EF, Hu C, Shaw PC (2023) Anti-influenza virus activities and mechanism of antrafenine analogs, European Journal of Medicinal Chemistry. 260,115775.
  2. Kan LL, Chan BC, Yue GG, Li P, Hon SS, Huang D, Tsang MS, Lau CB, Leung PC, Wong CK (2023) Immunoregulatory and Anti-cancer Activities of Combination Treatment of Novel Four-Herb Formula and Doxorubicin in 4T1-Breast Cancer Bearing Mice. Chin J Integr Med.  doi: 10.1007/s11655-023-3745-6.
  3. Ngai HL, Lee HK, Shaw PC (2023)DNA from herbs can be obtained from air and authenticated by polymerase chain reaction. Heliyon. 9:8.
  4. Kan LLY, Chan BCL, Leung PC, Wong CK (2023) Natural-Product-Derived Adjunctive Treatments to Conventional Therapy and Their Immunoregulatory Activities in Triple-Negative Breast Cancer. Molecules. 28: 5804.
  5. Shou JW, Shaw PC (2023) Berberine Reduces Lipid Accumulation in Obesity via Mediating Transcriptional Function of PPARδ. International Journal of Molecular Sciences. 24(14):11600.
  6. Chan BCL, Li P, Tsang MSM, Sung JCC, Kwong KWY, Zheng T, Hon SSM, Lau CP, Cheng W, Chen F, Lau CBS, Leung PC, Wong CK (2023) Creating a Vaccine-like Supplement against Respiratory Infection Using Recombinant Bacillus subtilis Spores Expressing SARS-CoV-2 Spike Protein with Natural Products. Molecules. 28(13):4996.
  7. Gao X, Chan PK, Wong KC, Ng RW, Yeung AC, Lui GC, Ling L, Hui DS, Huang D, Wong CK (2023) Characterization of METRNβ as a novel biomarker of Coronavirus disease 2019 severity and prognosis. Front Immunol. 31;14:1111920.
  8. Shou JW, Shaw PC. (2023). Berberine activates PPARδ and promotes gut microbiota-derived butyric acid to suppress hepatocellular carcinoma. Phytomedicine. 115:154842. 
  9. Wong KH, Siu TY, Tsang SSK, Kong BLH, Wu HY, But GWC, Hui JHL, Shaw PC, Lau DTW. (2023). The Complete Chloroplast Genomes of Nine Smilacaceae Species from Hong Kong: Inferring Infra- and Inter-Familial Phylogeny. International Journal of Molecular Sciences. 24(8):7460. 
  10. Chan JJS, Tang YS, Lo CY, Shaw PC. (2023). Functional Importance of the Hydrophobic Residue 362 in Influenza A PB1 Subunit. Viruses. 15(2):396.
  11. Wang F, Kong BL, Tang YS, Lee HK, Shaw PC. (2023). Bioassay guided isolation of caffeoylquinic acids from the leaves of Ilex pubescens Hook. et Arn. and investigation of their anti-influenza mechanism. Journal of Ethnopharmacology. 1:116322.
  12. Xiao M, Zhang T, Cao F, Liang W, Yang Y, Huang T, Tang YS, Liu B, Zhao X, Shaw, PC (2023). Anti-influenza properties of tiliroside isolated from Hibiscus mutabilis L. Journal of Ethnopharmacology, 303: 115918.
  13. Ngai HL, Kong BL, Lau DT, Shaw PC (2023) Differentiation of Lingxiaohua and Yangjinhua by chloroplast genome sequencing and DNA barcoding markers. Genome, 66(2): 21-33.
  14. But GW, Wu HY, Siu TY, Chan KT, Wong KH, Lau DT, Shaw PC (2023) Comparison of DNA extraction methods on CITES-listed timber species and application in species authentication of commercial products using DNA barcoding. Sci Rep. 13(1):151.
  15. Siu TY, Kong BLH, Wong KH, Wu HY, But GWC, Shaw PC, Lau DTW (2023). Characterization and phylogenetic analysis of the complete chloroplast genome of Emilia sonchifolia (L.) DC. Mitochondrial DNA Part B, 8(1), 20-22.



  1. Ling J, Chan CL, Ho CY, Gao X, Tsang SM, Leung PC, Hu JM, Wong CK (2022) The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-κB Signalling. Int J Mol Sci. 23;23(19):11195.
  2. Song Q, Cheng SW, Li D, Cheng H, Lai YS, Han Q, Wu HY, Shaw PC, Zuo Z (2022) Gut microbiota mediated hypoglycemic effect of Astragalus membranaceus polysaccharides in db/db mice. Front Pharmacol. 13:1043527.
  3. Xiao M, Zhang T, Cao F, Liang W, Yang Y, Huang T, Tang YS, Liu B, Zhao X, Shaw PC (2022) Anti-influenza properties of tiliroside isolated from Hibiscus mutabilis L. J Ethnopharmacol. 24:115918.
  4. Gao X, Wu G, Tsang MS, Huang D, Lam CW, Wong CK (2022) Novel insights into the role of anti-inflammatory IL-38 in immunity against infection. Cell Mol Immunol. 19(11):1322-1324.
  5. Tang YS, So WK, Ng KLA, Mok KPC, Shaw PC (2022) Interaction of Influenza A Nucleoprotein with Host hnRNP-C Is Implicated in Viral Replication. Int. J. Mol. Sci. 23, 13613.
  6. Zhang J, Deng Q, Liu X, Wu M, Ma Z, Shaw PC, Zhang Y, Cao H (2022) Molecular Identification of Commercial Fish Maws by DNA Sequencing of 16S rRNA and Cytochrome c Oxidase I Genes. J Food Prot. 1;85(10):1439-1445.
  7. Xiao M, Cao F, Huang T, Tang YS, Zhao X, Shaw  PC (2022) Urolithin M5 from the leaves of Canarium album (Lour.) DC. 2 Inhibits influenza virus by targeting neuraminidase. Molecules. 5;27(17):5724.
  8. Lu JQ, Shou JW, Lo KC, Tang YS, Shi WW, Shaw PC (2022) Pore-Forming Cardiotoxin VVA2 (Volvatoxin A2) Variant I82E/L86K Is an Atypical Duplex-Specific Nuclease. Toxins. 14(6):392.
  9. Wong KH, Wu HY, Kong BLH, But GWC, Siu TY, Hui JHL,  Shaw PC, Lau DTW (2022) Characterisation of the Complete Chloroplast Genomes of Seven Hyacinthus orientalis L. Cultivars: Insights into Cultivar Phylogeny. Horticulturae. 8(5): 453.
  10. Xiao M, Lim-Ho Kong B, Zhang Y, Yang Y, Lu J, Lee HK, Cao F, Shaw PC (2022) Anti-influenza mechanism of phenolic phytochemicals from Canarium album (Lour.) DC. leaf extract. J Ethnopharmacol. 292:115175.
  11. Siu TY, Wong KH, Kong BLH, Wu HY, But GWC, Shaw PC, Lau DTW (2022) The complete chloroplast genome of Iris speculatrix Hance, a rare and endangered plant native to Hong Kong. Mitochondrial DNA B Resour. 7(5):864-866.
  12. Wong KH, Kong BLH, Siu TY, Wu HY, But GW, Shaw PC, Lau DTW (2022) Complete chloroplast genomes of Asparagus aethiopicus L., A. densiflorus (Kunth) Jessop ‘Myers’, and A. cochinchinensis (Lour.) Merr.: Comparative and phylogenetic analysis with congenerics. PLoS One. 17(4):e0266376.
  13. Wu HY, Wong KH, Kong BLH, Siu TY, But GWC, Tsang SS, Lau DTW, Shaw PC (2022) Comparative Analysis of Chloroplast Genomes of Dalbergia Species for Identification and Phylogenetic Analysis. Plants (Basel). 11(9):1109.
  14. Lyu Y, Li D, Yuan X, Li Z, Zhang J, Ming X, Shaw PC, Zhang C, Kong APS, Zuo Z (2022) Effects of combination treatment with metformin and berberine on hypoglycemic activity and gut microbiota modulation in db/db mice. Phytomedicine. 101:154099.
  15. Kong BLH, Nong W, Wong KH, Law STS, So WL, Chan JJS, Zhang J, Lau TWD, Hui JHL, Shaw PC (2022) Chromosomal level genome of Ilex asprella and insight into antiviral triterpenoid pathway. Genomics. 114(3): 110366.
  16. Ngai HL, Yang X, Chu AJ, Harper R, Jacobsen ABJE, Lau DTW, Yu HY, Lee HK, Shaw PC (2022) Multi-methodological approach for the Quality assessment of Senecionis scandentis Herba (Qianliguang) in the herbal market. PLoS One. 17(4): e0267143.
  17. Wu HY, Shaw PC (2022) Strategies for molecular authentication of herbal products: from experimental design to data analysis. Chin Med. 17: 38.
  18. Xiao M, Kong BLH, Zhang Y, Yang Y, Lu J, Lee HK, Cao F, Shaw PC (2022) Anti-influenza mechanism of phenolic phytochemicals from Canarium album (Lour.) DC. leaf extract. J. Ethnopharmacol. 292:115175.
  19. Lu JQ, Wong KB, Shaw PC (2022) A Sixty-Year Research and Development of Trichosanthin, a Ribosome-Inactivating Protein. Toxins. 14: 178.
  20. Shou JW, Shaw PC (2022) Therapeutic Efficacies of Berberine against Neurological Disorders: An Update of Pharmacological Effects and Mechanisms. Cells. 11 (5): 796.
  21. Shou JW, Li XX, Tang YS, Lim-Ho Kong B, Wu HY, Xiao MJ, Cheung CK, Shaw PC (2022) Novel mechanistic insight on the neuroprotective effect of berberine: The role of PPARδ for antioxidant action. Free Radic Biol Med. 27:S0891-5849(22)00033-8.
  22. Ling J, Chan BCL, Tsang MSM, Gao X, Leung PC, Lam CWK, Hu JM, Wong CK (2022) Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine. Front. Med. 8:815075.
  23. Li P, Tsang MSM, Kan LLY,  Hou T, Hon SSM, Chan BCL, Chu IMT, Lam CWK, Leung PC, Wong CK (2022) The Immuno-Modulatory Activities of Pentaherbs Formula on Ovalbumin-Induced Allergic Rhinitis Mice via the Activation of Th1 and Treg Cells and Inhibition of Th2 and Th17 Cells. Molecules. 27:239.
  24. Gao X, Leung TF, Wong GWK, Ko WH, Cai M, He EJ, Chu IMT, Tsang MSM, Chan BCL, Ling J, Fan X, Lu L, Lam CWK, Wong CK (2022) Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma. Cell Mol Immunol.  19(2):245-259.


  1. Xu QQ, Shaw PC, Hu Z, Yang W, Ip SP, Xian YF, Lin ZX (2021) Comparison of the chemical constituents and anti-Alzheimer’s disease effects of Uncaria rhynchophylla and Uncaria tomentosa. Chin Med. 16(1):110.
  2. Yang H, Cheung MK, Yue GGL, Leung PC, Wong CK, Lau CBS (2021) Integrated Network Pharmacology Analysis and In Vitro Validation Revealed the Potential Active Components and Underlying Mechanistic Pathways of Herba Patriniae in Colorectal Cancer. Molecules. 26(19):6032.
  3. Lu JQ, Shi WW, Xiao MJ, Tang YS, Zheng YT, Shaw PC (2021) Lyophyllin, a Mushroom Protein from the Peptidase M35 Superfamily Is an RNA N-Glycosidase. Int. J. Mol. Sci. 22: 11598.
  4. Wu XX, Siu WS, Wat CL, Chan CL, Koon CM, Li X, Cheng W, Ma H, Tsang MSM, Lam CWK, Leung PC, Lau CBS, Wong CK (2021) Effects of topical application of a tri-herb formula on inflammatory dry-skin condition in mice with oxazolone-induced atopic dermatitis. Phytomedicine. 91:153691.
  5. Yik MHY, Taam Wong VCW, Wong TH, Shaw PC. (2021) HerBChain, a blockchain-based informative platform for quality assurance and quality control of herbal products. J. Tradit. Complement. Med. 11(6):598-600.
  6. Zheng T, Wong ECW, Yue GGL, Li XX, Wu KHY, Lau DTW, Shaw PC, Simmonds MSJ, Lau CBS (2021) Identification and quantification of tricin present in medicinal herbs, plant foods and by‑products using UPLC‑QTOF‑MS. Chemical Papers. 75:4579–4588.
  7. Li XX, Chen SG, Yue GGL, Kwok HF, Lee JKL, Zheng T, Shaw PC, Simmonds MSJ, Lau CBS (2021) Natural flavone tricin exerted anti-inflammatory activity in macrophage via NF-κB pathway and ameliorated acute colitis in mice. Phytomedicine. 90:153625.
  8. LyuY, Lin L, Xie Y, Li D,  Xiao M, Zhang Y, Cheung SCK, Shaw PC, Yang X, Chan PKS, Kong APS, Zuo Z (2021) Blood-Glucose-Lowering Effect of Coptidis Rhizoma Extracts From Different Origins via Gut Microbiota Modulation in db/db Mice. Front. Pharmacol. 12:1455.
  9. Tang YS, Xu ST, Chen YW, Wang JH, Shaw PC (2021) Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction. Nucleic Acids Res. 49(7):4144-4154.
  10. Siu TY, Yik MHY, Boufford DE, Shaw PC, Lau DTW (2021) Proposal to conserve the name Hedyotis diffusa (Oldenlandia diffusa, Scleromitrion diffusum) (Rubiaceae) with a conserved type. Taxon. 70(2):443–444.
  11. Kong BLH, Park HS, Lau TWD, Lin ZX, Yang TJ, Shaw PC (2021) Comparative analysis and phylogenetic investigation of Hong Kong Ilex chloroplast genomes. Sci. Rep. 11(1):5153.
  12. Wu HY, Chan KT, But GWC, Shaw PC (2021) Assessing the reliability of medicinal Dendrobium sequences in GenBank for botanical species identification. Sci. Rep. 11:3439.
  13. Yik MHY, Lo YT, Lin X, Sun W, Chan TF, Shaw PC (2021) Authentication of Hedyotis products by adaptor ligation-mediated PCR and metabarcoding. J Pharm Biomed Anal. 196:113920.
  14. Tsang MSM, Hou T, Chan BCL, Wong CK (2021) Immunological Roles of NLR in Allergic Diseases and Its Underlying Mechanisms. Int. J. Mol. Sci. 22:1507.
  15. Yik MHY, Kong BLH, Siu TY, Lau DTW, Cao H, Shaw PC (2021) Differentiation of Hedyotis diffusa and Common Adulterants Based on Chloroplast Genome Sequencing and DNA Barcoding Markers. Plants (Basel). 10(1): 161.
  16. Gao X, Chan PKS, Lui GCY, Hui DSC, Chu IMT, Sun X, Tsang MSM, Chan BCL, Lam CWK, Wong CK (2021) Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections. Cell Death Dis. 12(1):53.
  17. Yue GGL, Chan YY, Liu WJ, Gao S, Wong CW, Lee JKM, Lau KM, Lau CBS (2021) Effectiveness of Scutellaria barbata water extract on inhibiting colon tumor growth and metastasis in tumor-bearing mice. Phytother. Res. 35:361 -373.


  1. Chu M, Tsang MSM, He R, Lam CWK, Quan ZB, Wong CK (2020) The Active Compounds and Therapeutic Mechanisms of Pentaherbs Formula for Oral and Topical Treatment of Atopic Dermatitis Based on Network Pharmacology. Plants (Basel). 9(9):1166.
  2. Kan LLY, Liu D, Chan BCL, Tsang MSM, Hou T, Leung PC, Lam CWK, Wong CK (2020)The flavonoids of Sophora flavescens exerts anti-inflammatory activity via promoting autophagy of Bacillus Calmette-Guérin-stimulated macrophages. J Leukoc Biol. 108(5):1615-1629. 
  3. Tsang MSM, Wong CK (2020) Functional interaction between sensory neurons and mast cells in the early stage of house dust mite-induced type 2 inflammation and itch: a novel therapeutic target of allergic disease. Cell Mol Immunol. 17(9):899-900.
  4. Lin JB, Wu H, Liu YL, Shaw PC, Li PB (2020) N16 suppresses RANKL-mediated osteoclatogenesis by down-regulating RANK expression. Int J Biol Macromol. 151:1154-1162.
  5. Zhang TB, Lo CY, Xiao MJ, Cheng L, Mok CKP, Shaw PC (2020) Anti-influenza virus phytochemicals from Radix Paeoniae Alba and characterization of their neuraminidase inhibitory activities. J Ethnopharmacol. 253:112671.
  6. Yue GGL, Gao S, Lee JKM, Chan YY, Wong ECW, Zheng T, Li XX, Shaw PC, Simmonds MSJ, Lau CBS (2020) A Natural Flavone Tricin from Grains Can Alleviate Tumor Growth and Lung Metastasis in Colorectal Tumor Mice. Molecules. 25:3730.
  7. Tsang MS,Sun XY, Wong CK (2020) The Role of New IL-1 Family Members (IL-36 and IL-38) in Atopic Dermatitis, Allergic Asthma, and Allergic Rhinitis. Curr Allergy Asthma Rep. 20(8):40.
  8. But GWC, Wu HY, Shao KT, Shaw PC (2020) Rapid detection of CITES-listed shark fin species by loop-mediated isothermal amplification assay with potential for field use. Sci Rep. 10:4455.



Comments are closed.